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It is always best to have the area decontaminated by a professional, but for those wishing to perform the work personally, a respirator or a Hepa filter device should be worn when removing bat droppings. You should also wear an inexpensive plastic coverall, gloves and goggles. You may also wish to wear a headlamp in order to view the area you will be cleaning more properly. Protective wear may be purchased online or in some hardware and department stores.

Some professionals recommend lightly wetting the bat droppings to cut down on the amount of airborne spores while cleaning. Vacuum the bat guano up with a shop vacuum or other device that is not as likely to put as much dust back into the air as you are sucking up, making sure to fully remove any pockets of insect infestation you may find in the area. In worst-case scenarios, insulation and sheetrock may need to be removed in order to get to all of the droppings.
A coat of shellac will seal in most odor-causing compounds.
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